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Recent Publications

The Evoked Potential Operant Conditioning System (EPOCS): A Research Tool and an Emerging Therapy for Chronic Neuromuscular Disorders.
N Hill J, Gupta D, Eftekhar A, Brangaccio JA, Norton JJS, McLeod M, et al.. The Evoked Potential Operant Conditioning System (EPOCS): A Research Tool and an Emerging Therapy for Chronic Neuromuscular Disorders. J Vis Exp. 2022;(186).
Operant down-conditioning of the soleus H-reflex in people after stroke.
Thompson AK, Gill CR, Feng W, Segal RL. Operant down-conditioning of the soleus H-reflex in people after stroke. Front Rehabil Sci. 2022;3:859724.
Automated intraoperative central sulcus localization and somatotopic mapping using median nerve stimulation.
Xie T, Wu Z, Schalk G, Tong Y, Vato A, Raviv N, et al.. Automated intraoperative central sulcus localization and somatotopic mapping using median nerve stimulation. J Neural Eng. 2022;.
Soleus H-reflex modulation during a double-legged drop landing task.
Lyle MA, McLeod MM, Pouliot BA, Thompson AK. Soleus H-reflex modulation during a double-legged drop landing task. Exp Brain Res. 2022;240(4):1093-1103.
Neural oscillations during motor imagery of complex gait: an HdEEG study.
Putzolu M, Samogin J, Cosentino C, Mezzarobba S, Bonassi G, Lagravinese G, et al.. Neural oscillations during motor imagery of complex gait: an HdEEG study. Sci Rep. 2022;12(1):4314.
Dynamics of Oddball Sound Processing: Trial-by-Trial Modeling of ECoG Signals.
Lecaignard F, Bertrand R, Brunner P, Caclin A, Schalk G, Mattout J. Dynamics of Oddball Sound Processing: Trial-by-Trial Modeling of ECoG Signals. Front Hum Neurosci. 2022;15:794654.
A neural population selective for song in human auditory cortex
Norman-Haignere SV, Feather J, Boebinger D, Brunner P, Ritaccio A, McDermott JH, et al.. A neural population selective for song in human auditory cortex. Current Biology [Internet]. 2022;32:1470-1484.e12. https://www.sciencedirect.com/science/article/pii/S0960982222001312
A Voting-Enhanced Dynamic-Window-Length Classifier for SSVEP-Based BCIs.
Habibzadeh H, Norton JJS, Vaughan TM, Soyata T, Zois D-S. A Voting-Enhanced Dynamic-Window-Length Classifier for SSVEP-Based BCIs. IEEE Trans Neural Syst Rehabil Eng. 2021;29:1766-1773.
Recommendations for Responsible Development and Application of Neurotechnologies.
Goering S, Klein E, Sullivan LSpecker, Wexler A, Agüera Y Arcas B, Bi G, et al.. Recommendations for Responsible Development and Application of Neurotechnologies. Neuroethics. 2021;14(3):365-386.
Modulation in cortical excitability disrupts information transfer in perceptual-level stimulus processing.
Moheimanian L, Paraskevopoulou SE, Adamek M, Schalk G, Brunner P. Modulation in cortical excitability disrupts information transfer in perceptual-level stimulus processing. Neuroimage. 2021;243:118498.
Within-subject reaction time variability: Role of cortical networks and underlying neurophysiological mechanisms.
Paraskevopoulou SE, Coon WG, Brunner P, Miller KJ, Schalk G. Within-subject reaction time variability: Role of cortical networks and underlying neurophysiological mechanisms. Neuroimage. 2021;237:118127.
audiomath: A neuroscientist's sound toolkit.
N Hill J, Mooney SWJ, Prusky GT. audiomath: A neuroscientist's sound toolkit. Heliyon. 2021;7(2):e06236.
Can Operant Conditioning of EMG-Evoked Responses Help to Target Corticospinal Plasticity for Improving Motor Function in People With Multiple Sclerosis?
Thompson AK, Sinkjær T. Can Operant Conditioning of EMG-Evoked Responses Help to Target Corticospinal Plasticity for Improving Motor Function in People With Multiple Sclerosis?. Front Neurol. 2020;11:552.
Operant Condition of the Flexor Carpi Radialis H-reflex
Norton J, Vaughan T, Gemoets D, Heckman S, Toliou SD, Carp J, et al.. Operant Condition of the Flexor Carpi Radialis H-reflex. Archives of Physical Medicine and Rehabilitation [Internet]. 2020;101(12). https://www.archives-pmr.org/article/S0003-9993(20)31081-9/abstract
Breathable, large-area epidermal electronic systems for recording electromyographic activity during operant conditioning of H-reflex.
Kwon Y-T, Norton JJS, Cutrone A, Lim H-R, Kwon S, Choi JJ, et al.. Breathable, large-area epidermal electronic systems for recording electromyographic activity during operant conditioning of H-reflex. Biosens Bioelectron. 2020;165:112404.
Potential differences between monolingual and bilingual patients in approach and outcome after awake brain surgery.
ReFaey K, Tripathi S, Bhargav AG, Grewal SS, Middlebrooks EH, Sabsevitz DS, et al.. Potential differences between monolingual and bilingual patients in approach and outcome after awake brain surgery. J Neurooncol. 2020;148(3):587-598.
BCI-based sensorimotor rhythm training can affect individuated finger movements
McFarland DJ, Norman SL, Sarnacki WA, Wolbrecht ET, Reinkensmeyer DJ, Wolpaw JR. BCI-based sensorimotor rhythm training can affect individuated finger movements . Brain Computer Interface Society [Internet]. 2020;7(1). https://www.tandfonline.com/doi/abs/10.1080/2326263X.2020.1763060?journalCode=tbci20
Enhancing Communication for People in Late-Stage ALS Using an fNIRS-Based BCI System.
Borgheai SBahram, McLinden J, Zisk AHillary, Hosni SIsmail, Deligani RJafari, Abtahi M, et al.. Enhancing Communication for People in Late-Stage ALS Using an fNIRS-Based BCI System. IEEE Trans Neural Syst Rehabil Eng. 2020;28(5):1198-1207.
Brain-computer interfaces for people with amyotrophic lateral sclerosis
Vaughan T. Brain-computer interfaces for people with amyotrophic lateral sclerosis. Handbook of Clinical Neurology [Internet]. 2020;168. https://www.sciencedirect.com/science/article/pii/B9780444639349000044
Brain-computer interfaces: Definitions and principles
Wolpaw JR, Millán Jdel R, Ramsey NF. Brain-computer interfaces: Definitions and principles. Handbook of Clinical Neurology [Internet]. 2020;168. https://www.sciencedirect.com/science/article/pii/B9780444639349000020
iEEGview: an open-source multifunction GUI-based Matlab toolbox for localization and visualization of human intracranial electrodes.
Li G, Jiang S, Chen C, Brunner P, Wu Z, Schalk G, et al.. iEEGview: an open-source multifunction GUI-based Matlab toolbox for localization and visualization of human intracranial electrodes. J Neural Eng. 2019;17(1):016016.
An exploration of BCI performance variations in people with amyotrophic lateral sclerosis using longitudinal EEG data
Shahriari Y, Vaughan T, McCane L, Allison B, Wolpaw J, Krusienski D. An exploration of BCI performance variations in people with amyotrophic lateral sclerosis using longitudinal EEG data. Journal of Neural Engineering [Internet]. 2019;. https://iopscience.iop.org/article/10.1088/1741-2552/ab22ea
A quantitative method for evaluating cortical responses to electrical stimulation
Crowther LJ, Brunner P, Kapeller C, Guger C, Kamada K, Bunch ME, et al.. A quantitative method for evaluating cortical responses to electrical stimulation. Journal of Neuroscience Methods [Internet]. 2019;311:67 - 75. http://www.sciencedirect.com/science/article/pii/S0165027018302796
Rapid Identification of Cortical Connectivity During Functional Mapping
Crowther LJ, Brunner P, Ritaccio AL, Schalk G. Rapid Identification of Cortical Connectivity During Functional Mapping. American Epilepsy Society 72nd Annual Meeting. New Orleans, LA; 2018.
Optimal referencing for stereo-electroencephalographic (SEEG) recordings
Li G, Jiang S, Paraskevopoulou S, Wang M, Xu Y, Wu Z, et al.. Optimal referencing for stereo-electroencephalographic (SEEG) recordings. NeuroImage [Internet]. 2018;183:327-335. https://www.sciencedirect.com/science/article/pii/S1053811918307183
Creating an eyes-closed binary SSVEP-based brain-computer interface (BCI) for the bedside: A comparison of foveal centered and off-centered stimulus presentation
Vaughan TM, Aslam M, Zoltan B, Brunner P, Norton JJ, Carmack CS, et al.. Creating an eyes-closed binary SSVEP-based brain-computer interface (BCI) for the bedside: A comparison of foveal centered and off-centered stimulus presentation. 2018.
Towards operant conditioning of the flexor carpi radialis: Methods and initial results
Norton J, Eftekhar A, Heckman S, Barnes JH, McCane L, Wolpaw J. Towards operant conditioning of the flexor carpi radialis: Methods and initial results. Program No. 387.08. 2018 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. Online. 2018.
Combining H-reflex conditioning and locomotor training appears to enhance locomotor recovery in rats with incomplete spinal cord injury: Initial results
Chen XY, Chen L, Yang X, Wang Y, Chen Y, Wolpaw J. Combining H-reflex conditioning and locomotor training appears to enhance locomotor recovery in rats with incomplete spinal cord injury: Initial results. Program No. 387.12. 2018 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. Online. 2018.
Creating an eyes-closed binary SSVEP-based brain-computer interface (BCI) for the bedside: A comparison of foveal centered and off-centered stimulus presentation
Vaughan TM, Aslam M, Zoltan B, Brunner P, Norton JJ, Carmack CS, et al.. Creating an eyes-closed binary SSVEP-based brain-computer interface (BCI) for the bedside: A comparison of foveal centered and off-centered stimulus presentation. Program No. 225.17. 2018 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. Online. San Diego, CA; 2018.
Instantaneous voltage of electroencephalographic oscillatory activity: An alternative to power and phase measurements
Adamek M, Brunner P, Moheimanian L, Scherer R, Schalk G. Instantaneous voltage of electroencephalographic oscillatory activity: An alternative to power and phase measurements. Program No. 125.17. 2018 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. Online. San Diego, CA; 2018.
Controlling pre-movement sensorimotor rhythm can improve finger extension after stroke
Norman SL, McFarland DJ, Miner A, Cramer SC, Wolbrecht ET, Wolpaw J, et al.. Controlling pre-movement sensorimotor rhythm can improve finger extension after stroke. Journal of Neural Engineering [Internet]. 2018;15(5). http://stacks.iop.org/1741-2552/15/i=5/a=056026
Effects of Sensorimotor Rhythm Modulation on the Human Flexor Carpi Radialis H-Reflex
Thompson AK, Carruth H, Haywood R, Hill NJ, Sarnacki WA, McCane LM, et al.. Effects of Sensorimotor Rhythm Modulation on the Human Flexor Carpi Radialis H-Reflex. Frontiers in Neuroscience [Internet]. 2018;12. https://www.frontiersin.org/article/10.3389/fnins.2018.00505
Retraining Reflexes: Clinical Translation of Spinal Reflex Operant Conditioning
Eftekhar A, Norton JJS, McDonough CM, Wolpaw J. Retraining Reflexes: Clinical Translation of Spinal Reflex Operant Conditioning. Neurotherapeutics [Internet]. 2018;15(3):669-683. https://link.springer.com/article/10.1007/s13311-018-0643-2
Independent home use of a brain-computer interface by people with amyotrophic lateral sclerosis
Wolpaw J, Bedlack RS, Reda DJ, Ringer RJ, Banks PG, Vaughan TM, et al.. Independent home use of a brain-computer interface by people with amyotrophic lateral sclerosis. Neurology [Internet]. 2018;. http://n.neurology.org/content/neurology/early/2018/06/27/WNL.0000000000005812.full.pdf
Electrical Stimulation Mapping of the Brain: Basic Principles and Emerging Alternatives
Ritaccio A, Brunner P, Schalk G. Electrical Stimulation Mapping of the Brain: Basic Principles and Emerging Alternatives. Journal of Clinical Neurophysiology [Internet]. 2018;35(2):86-97. https://journals.lww.com/clinicalneurophys/Abstract/2018/03000/Electrical_Stimulation_Mapping_of_the_Brain__.2.aspx
Real-time detection and discrimination of visual perception using electrocorticographic signals
Kapeller C, Ogawa H, Schalk G, Kunii N, Coon WG, Scharinger J, et al.. Real-time detection and discrimination of visual perception using electrocorticographic signals. Journal of Neural Engineering [Internet]. 2018;15(3). http://iopscience.iop.org/article/10.1088/1741-2552/aaa9f6/pdf
Instantaneous voltage of electroencephalographic oscillatory activity: An alternative to power and phase measurements
Adamek M, Brunner P, Moheimanian L, Scherer R, Schalk G. Instantaneous voltage of electroencephalographic oscillatory activity: An alternative to power and phase measurements. Program No. 125.17. 2018 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience. Online. 2018.
Passive functional mapping of receptive language areas using electrocorticographic signals
Swift JR, Coon WG, Guger C, Brunner P, Bunch M, Lynch T, et al.. Passive functional mapping of receptive language areas using electrocorticographic signals. Clinical Neurophysiology [Internet]. 2018;129:2517 - 2524. http://www.sciencedirect.com/science/article/pii/S1388245718312288
The performance of 9–11-year-old children using an SSVEP-based BCI for target selection
Norton JJS, Mullins J, Alitz BE, Bretl T. The performance of 9–11-year-old children using an SSVEP-based BCI for target selection. Journal of Neural Engineering [Internet]. 2018;15:056012. http://stacks.iop.org/1741-2552/15/i=5/a=056012
Acquisition, maintenance, and therapeutic use of a simple motor skill
Norton JJS, Wolpaw J. Acquisition, maintenance, and therapeutic use of a simple motor skill. Current Opinion in Behavioral Sciences [Internet]. 2018;20:138 - 144. http://www.sciencedirect.com/science/article/pii/S235215461730219X
Encoding of Multiple Reward-Related Computations in Transient and Sustained High-Frequency Activity in Human OFC
Saez I, Lin J, Stolk A, Chang E, Parvizi J, Schalk G, et al.. Encoding of Multiple Reward-Related Computations in Transient and Sustained High-Frequency Activity in Human OFC. Current Biology [Internet]. 2018;28:2889 - 2899.e3. http://www.sciencedirect.com/science/article/pii/S0960982218309758
ECoG-Based BCIs
Gunduz A, Schalk G. ECoG-Based BCIs. In Brain–Computer Interfaces Handbook: Technological and Theoretical Advances. 2018. p. 297.
Perspectives on Brain–Computer Interfaces
Schalk G. Perspectives on Brain–Computer Interfaces. In Brain–Computer Interfaces Handbook. CRC Press; 2018. pp. 721–724.
BCI Software
Brunner P, Schalk G. BCI Software. In Brain–Computer Interfaces Handbook: Technological and Theoretical Advances. 2018. p. 323.
Overview
Overview

Registration is now open for NCAN's course on Translating Adaptive Neurotechnologies: Methodologies for Real-Time Interactions with the Nervous System to be held at the Stratton VA Medical Center in Albany, NY, on July 10-14, 2023. Learn more about this course here.

 
 
The National Center for Adaptive Neurotechnologies (NCAN), which is supported by the National Institute of Biomedical Imaging and Bioengineering, is the culmination of a unique research program that has developed over several decades. This program is founded on two major advances, one scientific and one technical. The scientific advance is the recognition that activity-dependent plasticity occurs continually throughout the central nervous system (CNS) and throughout life. The technical advance is the widespread availability of hardware and software that can support complex real-time interactions with the nervous system.
 
The scientists and engineers of NCAN have both contributed to and taken advantage of these advances; they have built a unique technical and procedural infrastructure that supports beneficial real-time interactions with the CNS. They are using this infrastructure to produce new scientific insights and novel therapeutic methods. They are realizing adaptive systems that interact with the nervous system in real time to achieve three important goals: guiding beneficial CNS plasticity; restoring lost neuromuscular functions; and characterizing and localizing brain processes, both spatially and temporally.

 
These three goals and the adaptive systems dedicated to them are the foci of NCAN ’s three technical research and development (TR&D) projects. These projects use a suite of related hardware/software platforms and real-time analysis methods that are continually updated and expanded. Through energetic interactions with a set of outstanding collaborators, NCAN personnel are developing and using each project as a basic research tool and are also translating it into important new clinical applications. NCAN is thereby increasing understanding of CNS function and dysfunction; and it is realizing effective new therapies for a wide range of devastating neurological disorders.
 
In addition, NCAN provides an extensive program of training and dissemination activities and resources. Our goal is to create and maintain an ecosystem of people, knowledge, and hardware and software that enables and promotes the widespread use and further development of adaptive technologies by scientists, engineers, and clinicians to address important scientific and clinical problems. This program includes training courses and workshops, presentations at meetings and institutions, internships and other opportunities to work with NCAN scientists and engineers, software and hardware resources, training manuals, technical support mechanisms, and promotion of uniform hardware/software standards.
 
For questions, contact us at admin@neurotechcenter.org.
 
The National Center for Adaptive Neurotechnologies is part of the Stratton VA Medical Center in Albany, NY; its grant support is overseen by the Albany Research Institute, Inc., a not-for profit corporation organized under the New York State not-for-profit Corporation Law. It is exempt under Section 501(c) (3) of the Internal Revenue Service Code.

 

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