Reflex conditioning: a new strategy for improving motor function after spinal cord injury.

TitleReflex conditioning: a new strategy for improving motor function after spinal cord injury.
Publication TypeJournal Article
Year of Publication2010
AuthorsChen, XY, Chen, Y, Wang, Y, Thompson, A, Carp, JS, Segal, RL, Wolpaw, J
JournalAnnals of the New York Academy of Sciences
Volume1198 Suppl 1
PaginationE12–E21
Date Published06/2010
ISSN1749-6632
KeywordsH-Reflex, learning and memory, Locomotion, plasticity, reflex conditioning, Rehabilitation, spinal cord injury
Abstract

Spinal reflex conditioning changes reflex size, induces spinal cord plasticity, and modifies locomotion. Appropriate reflex conditioning can improve walking in rats after spinal cord injury (SCI). Reflex conditioning offers a new therapeutic strategy for restoring function in people with SCI. This approach can address the specific deficits of individuals with SCI by targeting specific reflex pathways for increased or decreased responsiveness. In addition, once clinically significant regeneration can be achieved, reflex conditioning could provide a means of reeducating the newly (and probably imperfectly) reconnected spinal cord.

URLhttp://www.ncbi.nlm.nih.gov/pubmed/20590534
DOI10.1111/j.1749-6632.2010.05565.x

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