TY - JOUR T1 - A motor association area in the depths of the central sulcus. JF - Nat Neurosci Y1 - 2023 A1 - Jensen, Michael A A1 - Huang, Harvey A1 - Valencia, Gabriela Ojeda A1 - Klassen, Bryan T A1 - van den Boom, Max A A1 - Kaufmann, Timothy J A1 - Schalk, Gerwin A1 - Brunner, Peter A1 - Worrell, Gregory A A1 - Hermes, Dora A1 - Miller, Kai J KW - Brain Mapping KW - Motor Cortex KW - Movement AB -

Cells in the precentral gyrus directly send signals to the periphery to generate movement and are principally organized as a topological map of the body. We find that movement-induced electrophysiological responses from depth electrodes extend this map three-dimensionally throughout the gyrus. Unexpectedly, this organization is interrupted by a previously undescribed motor association area in the depths of the midlateral aspect of the central sulcus. This 'Rolandic motor association' (RMA) area is active during movements of different body parts from both sides of the body and may be important for coordinating complex behaviors.

VL - 26 IS - 7 ER - TY - CONF T1 - Three cases of feature correlation in an electrocorticographic BCI. T2 - Engineering in Medicine and Biology Society, 2008. Y1 - 2008 A1 - Miller, Kai J A1 - Blakely, Timothy A1 - Gerwin Schalk A1 - den Nijs, Marcel A1 - Rao, Rajesh PN A1 - Ojemann, Jeffrey G KW - Adolescent KW - Adult KW - Algorithms KW - automated pattern recognition KW - control systems KW - decorrelation KW - Electrocardiography KW - Electrodes KW - Electroencephalography KW - evoked motor potentials KW - Feedback KW - Female KW - frequency KW - hospitals KW - Humans KW - Male KW - Middle Aged KW - Motor Cortex KW - Signal Processing KW - Statistics as Topic KW - Task Performance and Analysis KW - Tongue KW - User-Computer Interface AB - Three human subjects participated in a closed-loop brain computer interface cursor control experiment mediated by implanted subdural electrocorticographic arrays. The paradigm consisted of several stages: baseline recording, hand and tongue motor tasks as the basis for feature selection, two closed-loop one-dimensional feedback experiments with each of these features, and a two-dimensional feedback experiment using both of the features simultaneously. The two selected features were simple channel and frequency band combinations associated with change during hand and tongue movement. Inter-feature correlation and cross-correlation between features during different epochs of each task were quantified for each stage of the experiment. Our anecdotal, three subject, result suggests that while high correlation between horizontal and vertical control signal can initially preclude successful two-dimensional cursor control, a feedback-based learning strategy can be successfully employed by the subject to overcome this limitation and progressively decorrelate these control signals. JF - Engineering in Medicine and Biology Society, 2008. PB - IEEE CY - Vancouver, BC UR - http://www.ncbi.nlm.nih.gov/pubmed/19163918 ER -