TY - JOUR T1 - SPIRE: the SPIDER reconstruction engine. JF - J Struct Biol Y1 - 2007 A1 - Baxter, Bill A1 - Leith, ArDean A1 - Frank, Joachim KW - Computational Biology KW - Image Processing, Computer-Assisted KW - Software KW - Software Design AB -

SPIRE is a Python program written to modernize the user interaction with SPIDER, the image processing system for electron microscopical reconstruction projects. SPIRE provides a graphical user interface (GUI) to SPIDER for executing batch files of SPIDER commands. It also lets users quickly view the status of a project by showing the last batch files that were run, as well as the data files that were generated. SPIRE handles the flexibility of the SPIDER programming environment through configuration files: XML-tagged documents that describe the batch files, directory trees, and presentation of the GUI for a given type of reconstruction project. It also provides the capability to connect to a laboratory database, for downloading parameters required by batch files at the start of a project, and uploading reconstruction results at the end of a project.

VL - 157 UR - http://www.ncbi.nlm.nih.gov/pubmed/17055743 IS - 1 ER -