03177nas a2200493 4500008004100000022001400041245012000055210006900175260001200244300001200256490000800268520172300276653001801999653002002017653001502037653001102052653002202063653001102085653001102096653001402107653001302121653000902134653001602143653003102159653001402190653002602204653001302230653001802243653001602261100001802277700002302295700002102318700002302339700002602362700002402388700001802412700001902430700001402449700002202463700002202485700002602507700003102533856011902564 2020 eng d a1573-737300aPotential differences between monolingual and bilingual patients in approach and outcome after awake brain surgery.0 aPotential differences between monolingual and bilingual patients c07/2020 a587-5980 v1483 a

INTRODUCTION: 20.8% of the United States population and 67% of the European population speak two or more languages. Intraoperative different languages, mapping, and localization are crucial. This investigation aims to address three questions between BL and ML patients: (1) Are there differences in complications (i.e. seizures) and DECS techniques during intra-operative brain mapping? (2) Is EOR different? and (3) Are there differences in the recovery pattern post-surgery?

METHODS: Data from 56 patients that underwent left-sided awake craniotomy for tumors infiltrating possible dominant hemisphere language areas from September 2016 to June 2019 were identified and analyzed in this study; 14 BL and 42 ML control patients. Patient demographics, education level, and the age of language acquisition were documented and evaluated. fMRI was performed on all participants.

RESULTS: 0 (0%) BL and 3 (7%) ML experienced intraoperative seizures (P = 0.73). BL patients received a higher direct DECS current in comparison to the ML patients (average = 4.7, 3.8, respectively, P = 0.03). The extent of resection was higher in ML patients in comparison to the BL patients (80.9 vs. 64.8, respectively, P = 0.04). The post-operative KPS scores were higher in BL patients in comparison to ML patients (84.3, 77.4, respectively, P = 0.03). BL showed lower drop in post-operative KPS in comparison to ML patients (- 4.3, - 8.7, respectively, P = 0.03).

CONCLUSION: We show that BL patients have a lower incidence of intra-operative seizures, lower EOR, higher post-operative KPS and tolerate higher DECS current, in comparison to ML patients.

10aBrain Mapping10aBrain Neoplasms10aCraniotomy10aFemale10aFollow-Up Studies10aGlioma10aHumans10aIncidence10aLanguage10aMale10aMiddle Aged10aMonitoring, Intraoperative10aPrognosis10aRetrospective Studies10aSeizures10aUnited States10aWakefulness1 aReFaey, Karim1 aTripathi, Shashwat1 aBhargav, Adip, G1 aGrewal, Sanjeet, S1 aMiddlebrooks, Erik, H1 aSabsevitz, David, S1 aJentoft, Mark1 aBrunner, Peter1 aWu, Adela1 aTatum, William, O1 aRitaccio, Anthony1 aChaichana, Kaisorn, L1 aQuinones-Hinojosa, Alfredo uhttps://www.neurotechcenter.org/publications/2020/potential-differences-between-monolingual-and-bilingual-patients02106nas a2200421 4500008004100000022001400041245009000055210006900145260001200214300001100226490000700237520091200244653001001156653001801166653001601184653003301200653002701233653001301260653001101273653001801284653002801302100001801330700002401348700001901372700002701391700002001418700002201438700002001460700002301480700001601503700002001519700001301539700001901552700002201571700002401593700001901617856004801636 2011 eng d a1525-506900aProceedings of the Second International Workshop on Advances in Electrocorticography.0 aProceedings of the Second International Workshop on Advances in  c12/2011 a641-500 v223 a

The Second International Workshop on Advances in Electrocorticography (ECoG) was convened in San Diego, CA, USA, on November 11-12, 2010. Between this meeting and the inaugural 2009 event, a much clearer picture has been emerging of cortical ECoG physiology and its relationship to local field potentials and single-cell recordings. Innovations in material engineering are advancing the goal of a stable long-term recording interface. Continued evolution of ECoG-driven brain-computer interface technology is determining innovation in neuroprosthetics. Improvements in instrumentation and statistical methodologies continue to elucidate ECoG correlates of normal human function as well as the ictal state. This proceedings document summarizes the current status of this rapidly evolving field.

10aBrain10aBrain Mapping10aBrain Waves10aDiagnosis, Computer-Assisted10aElectroencephalography10aEpilepsy10aHumans10aUnited States10aUser-Computer Interface1 aRitaccio, A L1 aBoatman-Reich, Dana1 aBrunner, Peter1 aCervenka, Mackenzie, C1 aCole, Andrew, J1 aCrone, Nathan, E.1 aDuckrow, Robert1 aKorzeniewska, Anna1 aLitt, Brian1 aMiller, John, W1 aMoran, D1 aParvizi, Josef1 aViventi, Jonathan1 aWilliams, Justin, C1 aSchalk, Gerwin uhttp://www.ncbi.nlm.nih.gov/pubmed/22036287