02204nas a2200469 4500008004100000022001400041245010100055210006900156260001200225300000900237490000700246520081300253653001001066653002001076653001801096653001001114653002001124653003301144653002701177653001601204653001301220653001101233653003101244653003101275653002001306653001801326653001201344653001701356653001601373653003001389653001301419653003201432653004901464653002401513653003801537100002501575700001701600700002201617700002301639710002401662856004801686 2009 eng d a1525-506900aAdvances in the application of technology to epilepsy: the CIMIT/NIO Epilepsy Innovation Summit.0 aAdvances in the application of technology to epilepsy the CIMITN c09/2009 a3-460 v163 a

In 2008, a group of clinicians, scientists, engineers, and industry representatives met to discuss advances in the application of engineering technologies to the diagnosis and treatment of patients with epilepsy. The presentations also provided a guide for further technological development, specifically in the evaluation of patients for epilepsy surgery, seizure onset detection and seizure prediction, intracranial treatment systems, and extracranial treatment systems. This article summarizes the discussions and demonstrates that cross-disciplinary interactions can catalyze collaborations between physicians and engineers to address and solve many of the pressing unmet needs in epilepsy.

10aAdult10aAnticonvulsants10aBrain Mapping10aChild10aDrug Resistance10aElectric Stimulation Therapy10aElectroencephalography10aEngineering10aEpilepsy10aHumans10aMagnetic Resonance Imaging10aMedical Laboratory Science10aMicroelectrodes10aNanoparticles10aNeurons10aNeurosurgery10aNeurotoxins10aPredictive Value of Tests10aSeizures10aSpectroscopy, Near-Infrared10aTomography, Emission-Computed, Single-Photon10aTomography, Optical10aTranscranial Magnetic Stimulation1 aSchachter, Steven, C1 aGuttag, John1 aSchiff, Steven, J1 aSchomer, Donald, L1 aSummit Contributors uhttp://www.ncbi.nlm.nih.gov/pubmed/1978022502662nas a2200409 4500008004100000022001400041245008400055210006900139260001200208300001000220490000600230520153900236653001501775653001001790653001801800653003701818653002001855653002401875653002601899653002701925653001301952653001101965653001101976653000901987653001301996653002802009100001902037700001602056700002602072700002002098700001602118700001702134700001302151700002102164700001902185856004802204 2008 eng d a1741-256000aTwo-dimensional movement control using electrocorticographic signals in humans.0 aTwodimensional movement control using electrocorticographic sign c03/2008 a75-840 v53 a

We show here that a brain-computer interface (BCI) using electrocorticographic activity (ECoG) and imagined or overt motor tasks enables humans to control a computer cursor in two dimensions. Over a brief training period of 12-36 min, each of five human subjects acquired substantial control of particular ECoG features recorded from several locations over the same hemisphere, and achieved average success rates of 53-73% in a two-dimensional four-target center-out task in which chance accuracy was 25%. Our results support the expectation that ECoG-based BCIs can combine high performance with technical and clinical practicality, and also indicate promising directions for further research.

10aAdolescent10aAdult10aBrain Mapping10aData Interpretation, Statistical10aDrug Resistance10aElectrocardiography10aElectrodes, Implanted10aElectroencephalography10aEpilepsy10aFemale10aHumans10aMale10aMovement10aUser-Computer Interface1 aSchalk, Gerwin1 aMiller, K J1 aAnderson, Nicholas, R1 aWilson, Adam, J1 aSmyth, Matt1 aOjemann, J G1 aMoran, D1 aWolpaw, Jonathan1 aLeuthardt, E C uhttp://www.ncbi.nlm.nih.gov/pubmed/18310813