01388nas a2200205   4500008004100000022001400041245005900055210005600114260001200170300001400182490000800196520081100204653002801015100001501043700001901058700001501077700002101092700002101113856004801134       2001                        eng d  a0033-290900aBrain-computer communication: unlocking the locked in.0 aBraincomputer communication unlocking the locked in  c05/2001  a358–3750 v1273 aWith the increasing efficiency of life-support systems and better intensive care, more patients survive severe injuries of the brain and spinal cord. Many of these patients experience locked-in syndrome: The active mind is locked in a paralyzed body. Consequently, communication is extremely restricted or impossible. A muscle-independent communication channel overcomes this problem and is realized through a brain-computer interface, a direct connection between brain and computer. The number of technically elaborated brain-computer interfaces is in contrast with the number of systems used in the daily life of locked-in patients. It is hypothesized that a profound knowledge and consideration of psychological principles are necessary to make brain-computer interfaces feasible for locked-in patients.10aUser-Computer Interface1 aKübler, A1 aKotchoubey, B.1 aKaiser, J.1 aWolpaw, Jonathan1 aBirbaumer, Niels  uhttp://www.ncbi.nlm.nih.gov/pubmed/11393301