07936nas a2200361 4500008004100000022001400041245009600055210006900151260001200220300001100232490000800243520694900251653001507200653001007215653002807225653002007253653001007273653002507283653002407308653001107332653001107343653000907354653001607363653001907379653001607398100001607414700001907430700002207449700001707471700001707488700002107505856004807526 2010 eng d a1091-649000aCortical activity during motor execution, motor imagery, and imagery-based online feedback.0 aCortical activity during motor execution motor imagery and image c03/2010 a4430-50 v1073 a

Imagery of motor movement plays an important role in learning of complex motor skills, from learning to serve in tennis to perfecting a pirouette in ballet. What and where are the neural substrates that underlie motor imagery-based learning? We measured electrocorticographic cortical surface potentials in eight human subjects during overt action and kinesthetic imagery of the same movement, focusing on power in "high frequency" (76-100 Hz) and "low frequency" (8-32 Hz) ranges. We quantitatively establish that the spatial distribution of local neuronal population activity during motor imagery mimics the spatial distribution of activity during actual motor movement. By comparing responses to electrocortical stimulation with imagery-induced cortical surface activity, we demonstrate the role of primary motor areas in movement imagery. The magnitude of imagery-induced cortical activity change was approximately 25% of that associated with actual movement. However, when subjects learned to use this imagery to control a computer cursor in a simple feedback task, the imagery-induced activity change was significantly augmented, even exceeding that of overt movement.

10aAdolescent10aAdult10aBiofeedback, Psychology10aCerebral Cortex10aChild10aElectric Stimulation10aElectrocardiography10aFemale10aHumans10aMale10aMiddle Aged10aMotor Activity10aYoung Adult1 aMiller, K J1 aSchalk, Gerwin1 aFetz, Eberhard, E1 aNijs, Marcel1 aOjemann, J G1 aRao, Rajesh, P N uhttp://www.ncbi.nlm.nih.gov/pubmed/2016008401983nas a2200373 4500008004100000022001400041245011800055210006900173260000900242300001100251490000900262520077500271653001501046653002401061653003001085653001101115653000901126653003501135653003201170653002301202653003101225653003201256653002801288653001801316100002001334700001701354700001901371700002001390700002401410700001701434700001701451700002101468856012001489 2009 eng d a1557-170X00aDetection of spontaneous class-specific visual stimuli with high temporal accuracy in human electrocorticography.0 aDetection of spontaneous classspecific visual stimuli with high  c2009 a6465-80 v20093 aMost brain-computer interface classification experiments from electrical potential recordings have been focused on the identification of classes of stimuli or behavior where the timing of experimental parameters is known or pre-designated. Real world experience, however, is spontaneous, and to this end we describe an experiment predicting the occurrence, timing, and types of visual stimuli perceived by a human subject from electrocorticographic recordings. All 300 of 300 presented stimuli were correctly detected, with a temporal precision of order 20 ms. The type of stimulus (face/house) was correctly identified in 95% of these cases. There were approximately 20 false alarm events, corresponding to a late 2nd neuronal response to a previously identified event.10aAlgorithms10aElectrocardiography10aEvoked Potentials, Visual10aHumans10aMale10aPattern Recognition, Automated10aPattern Recognition, Visual10aPhotic Stimulation10aReproducibility of Results10aSensitivity and Specificity10aUser-Computer Interface10aVisual Cortex1 aMiller, John, W1 aHermes, Dora1 aSchalk, Gerwin1 aRamsey, Nick, F1 aJagadeesh, Bharathi1 aNijs, Marcel1 aOjemann, J G1 aRao, Rajesh, P N uhttps://www.neurotechcenter.org/publications/2009/detection-spontaneous-class-specific-visual-stimuli-high-temporal02352nas a2200445 4500008004100000245007200041210006900113260003300182520109300215653001501308653001001323653001501333653003401348653002001382653001801402653002401420653001501444653002701459653002801486653001301514653001101527653001401538653001401552653001101566653000901577653001601586653001701602653002201619653002401641653003401665653001101699653002801710100001901738700002101757700001901778700001701797700002001814700002401834856004801858 2008 eng d00aThree cases of feature correlation in an electrocorticographic BCI.0 aThree cases of feature correlation in an electrocorticographic B aVancouver, BCbIEEEc08/20083 aThree human subjects participated in a closed-loop brain computer interface cursor control experiment mediated by implanted subdural electrocorticographic arrays. The paradigm consisted of several stages: baseline recording, hand and tongue motor tasks as the basis for feature selection, two closed-loop one-dimensional feedback experiments with each of these features, and a two-dimensional feedback experiment using both of the features simultaneously. The two selected features were simple channel and frequency band combinations associated with change during hand and tongue movement. Inter-feature correlation and cross-correlation between features during different epochs of each task were quantified for each stage of the experiment. Our anecdotal, three subject, result suggests that while high correlation between horizontal and vertical control signal can initially preclude successful two-dimensional cursor control, a feedback-based learning strategy can be successfully employed by the subject to overcome this limitation and progressively decorrelate these control signals.10aAdolescent10aAdult10aAlgorithms10aautomated pattern recognition10acontrol systems10adecorrelation10aElectrocardiography10aElectrodes10aElectroencephalography10aevoked motor potentials10aFeedback10aFemale10afrequency10ahospitals10aHumans10aMale10aMiddle Aged10aMotor Cortex10aSignal Processing10aStatistics as Topic10aTask Performance and Analysis10aTongue10aUser-Computer Interface1 aMiller, Kai, J1 aBlakely, Timothy1 aSchalk, Gerwin1 aNijs, Marcel1 aRao, Rajesh, PN1 aOjemann, Jeffrey, G uhttp://www.ncbi.nlm.nih.gov/pubmed/1916391802177nas a2200361 4500008004100000022001400041245007200055210006900127260000900196300001200205520109300217653001501310653001001325653001501335653002401350653002901374653001101403653001101414653000901425653001601434653001701450653003501467653002401502653003401526653002801560100002001588700002101608700001901629700001701648700002101665700001701686856011201703 2008 eng d a1557-170X00aThree cases of feature correlation in an electrocorticographic BCI.0 aThree cases of feature correlation in an electrocorticographic B c2008 a5318-213 aThree human subjects participated in a closed-loop brain computer interface cursor control experiment mediated by implanted subdural electrocorticographic arrays. The paradigm consisted of several stages: baseline recording, hand and tongue motor tasks as the basis for feature selection, two closed-loop one-dimensional feedback experiments with each of these features, and a two-dimensional feedback experiment using both of the features simultaneously. The two selected features were simple channel and frequency band combinations associated with change during hand and tongue movement. Inter-feature correlation and cross-correlation between features during different epochs of each task were quantified for each stage of the experiment. Our anecdotal, three subject, result suggests that while high correlation between horizontal and vertical control signal can initially preclude successful two-dimensional cursor control, a feedback-based learning strategy can be successfully employed by the subject to overcome this limitation and progressively decorrelate these control signals.10aAdolescent10aAdult10aAlgorithms10aElectrocardiography10aEvoked Potentials, Motor10aFemale10aHumans10aMale10aMiddle Aged10aMotor Cortex10aPattern Recognition, Automated10aStatistics as Topic10aTask Performance and Analysis10aUser-Computer Interface1 aMiller, John, W1 aBlakely, Timothy1 aSchalk, Gerwin1 aNijs, Marcel1 aRao, Rajesh, P N1 aOjemann, J G uhttps://www.neurotechcenter.org/publications/2008/three-cases-feature-correlation-electrocorticographic-bci