02354nas a2200157   4500008004100000022001400041245011600055210006900171260001200240300001400252490000700266520182800273100002602101700002102127856004802148       2005                        eng d  a1534-432000aSensorimotor rhythm-based brain-computer interface (BCI): feature selection by regression improves performance.0 aSensorimotor rhythmbased braincomputer interface BCI feature sel  c09/2005  a372–3790 v133 aPeople can learn to control electroencephalogram (EEG) features consisting of sensorimotor rhythm amplitudes and can use this control to move a cursor in one or two dimensions to a target on a screen. In the standard one-dimensional application, the cursor moves horizontally from left to right at a fixed rate while vertical cursor movement is continuously controlled by sensorimotor rhythm amplitude. The right edge of the screen is divided among 2-6 targets, and the user's goal is to control vertical cursor movement so that the cursor hits the correct target when it reaches the right edge. Up to the present, vertical cursor movement has been a linear function of amplitude in a specific frequency band [i.e., 8-12 Hz (mu) or 18-26 Hz (beta)] over left and/or right sensorimotor cortex. The present study evaluated the effect of controlling cursor movement with a weighted combination of these amplitudes in which the weights were determined by an regression algorithm on the basis of the user's past performance. Analyses of data obtained from a representative set of trained users indicated that weighted combinations of sensorimotor rhythm amplitudes could support cursor control significantly superior to that provided by a single feature. Inclusion of an interaction term further improved performance. Subsequent online testing of the regression algorithm confirmed the improved performance predicted by the offline analyses. The results demonstrate the substantial value for brain-computer interface applications of simple multivariate linear algorithms. In contrast to many classification algorithms, such linear algorithms can easily incorporate multiple signal features, can readily adapt to changes in the user's control of these features, and can accommodate additional targets without major modifications.1 aMcFarland, Dennis, J.1 aWolpaw, Jonathan  uhttp://www.ncbi.nlm.nih.gov/pubmed/16200760