@article {4480,
	title = {Unexpected sound omissions are signaled in human posterior superior temporal gyrus: an intracranial study},
	journal = {Cereb Cortex},
	volume = {33},
	year = {2023},
	month = {07/2023},
	pages = {8837{\textendash}8848},
	abstract = {Context modulates sensory neural activations enhancing perceptual and behavioral performance and reducing prediction errors. However, the mechanism of when and where these high-level expectations act on sensory processing is unclear. Here, we isolate the effect of expectation absent of any auditory evoked activity by assessing the response to omitted expected sounds. Electrocorticographic signals were recorded directly from subdural electrode grids placed over the superior temporal gyrus (STG). Subjects listened to a predictable sequence of syllables, with some infrequently omitted. We found high-frequency band activity (HFA, 70-170 Hz) in response to omissions, which overlapped with a posterior subset of auditory-active electrodes in STG. Heard syllables could be distinguishable reliably from STG, but not the identity of the omitted stimulus. Both omission- and target-detection responses were also observed in the prefrontal cortex. We propose that the posterior STG is central for implementing predictions in the auditory environment. HFA omission responses in this region appear to index mismatch-signaling or salience detection processes.},
	author = {Cho, H. and Fonken, Y. M. and Adamek, M. and Jimenez, R. and Lin, J. J. and Schalk, G. and Knight, R. T. and Brunner, P.}
}
