@article {3231,
	title = {Time course of H-reflex conditioning in the rat.},
	journal = {Neuroscience letters},
	volume = {302},
	year = {2001},
	month = {04/2001},
	pages = {85{\textendash}88},
	abstract = {This study sought to define the course of operantly conditioned change in the rat soleus H-reflex and to determine whether, like H-reflex conditioning and spinal stretch reflex conditioning in the monkey, it develops in distinct phases. Data from 33 rats in which the right soleus H-reflex was trained up (i.e. HRup mode) and 38 in which it was trained down (i.e. HRdown mode) were averaged to define the courses of H-reflex increase and decrease. In HRup rats, the H-reflex showed a large phase I increase within the first 2 days followed by gradual phase II increase that continued for weeks. In HRdown rats, the H-reflex appeared to show a small phase I decrease and then showed a gradual phase II decrease over weeks. In combination with other recent work, the data suggest that H-reflex conditioning begins with a rapid mode-appropriate alteration in corticospinal tract influence over the spinal arc of the H-reflex, which causes phase I change, and that the continuation of this altered influence induces gradual spinal cord plasticity that is responsible for phase II change. The results further establish the similarity of H-reflex conditioning in primates and rats. Thus, they encourage efforts to produce a single coherent model of the phenomenon based on data from the two species and indicate the potential clinical relevance of the rat data.},
	keywords = {conditioning, Learning, Memory, plasticity, rat, Reflex, Spinal Cord},
	issn = {0304-3940},
	doi = {10.1016/S0304-3940(01)01658-5},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/11290393},
	author = {Xiang Yang Chen and Lu Chen and Jonathan Wolpaw}
}
