@article {3162, title = {Effects of chronic nerve cuff and intramuscular electrodes on rat triceps surae motor units.}, journal = {Neuroscience letters}, volume = {312}, year = {2001}, month = {10/2001}, pages = {1{\textendash}4}, abstract = {In order to assess the long-term effects of implanted electrodes on motor unit properties, we studied triceps surae (TS) motor units in rats implanted for 3-10 months with a tibial nerve cuff electrode for H-reflex elicitation and intramuscular electrodes for recording TS electromyographic activity. Motor units with sag from implanted rats displayed greater tetanic force than those from unimplanted rats. Motor units without sag had shorter twitch contraction times. This disrupted the relationship between sag and contraction time that was always present in unimplanted rats. These differences were consistent with a small degree of muscle denervation and subsequent reinnervation. Further analyses ascribed this effect to the nerve cuff rather than to the intramuscular electrodes. Comparable changes in motor unit properties may occur in humans with implanted nerve cuffs.}, keywords = {chronic recording, contraction time, H-Reflex, implanted electrodes, motor units, nerve cuff, reinnervation, sag}, issn = {0304-3940}, doi = {10.1016/S0304-3940(01)02183-8}, url = {http://www.ncbi.nlm.nih.gov/pubmed/11578831}, author = {Jonathan S. Carp and Xiang Yang Chen and Sheikh, H. and Jonathan Wolpaw} }