TY - JOUR T1 - Memory traces in spinal cord produced by H-reflex conditioning: effects of post-tetanic potentiation. JF - Neuroscience letters Y1 - 1989 A1 - Jonathan Wolpaw A1 - Jonathan S. Carp A1 - Lee, C. L. KW - conditioning KW - Learning KW - Memory KW - motoneuron KW - potentiation KW - primate KW - spinal reflex AB - Operant conditioning of the wholly spinal, largely monosynaptic triceps surae H-reflex in monkeys causes changes in lumbosacral spinal cord that persist after removal of supraspinal influence. We evaluated the interaction between post-tetanic potentiation and these memory traces. Animals in which the triceps surae H-reflex in one leg had been increased or decreased by conditioning were deeply anesthetized, and monosynaptic reflexes to L6-S1 dorsal root stimulation were recorded before and after tetanization from both legs for 3 days after thoracic cord transection. Animals remained anesthetized throughout and were sacrificed by overdose. Reflex asymmetries consistent with the effect of H-reflex conditioning were present after transection and persisted through the 3 days of study. Tetanization affected conditioned leg and control leg reflexes similarly. This finding suggests that, while post-tetanic potentiation and probably H-reflex conditioning alter Ia synaptic transmission, the two phenomena have different mechanisms. VL - 103 UR - http://www.ncbi.nlm.nih.gov/pubmed/2779852 ER -